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Muscle Building Supplements
Muscle Building Supplements -
BullWorker's 247BodyBuilder is the ultimate
natural muscle building supplement which stimulates and enhances your body's
natural GH growth hormone levels resulting in bigger, stronger more powerful
muscles with lower levels of body fat. Muscle building is not the overly
complex process that many claim it to be. Train hard with maximum intensity
then allow your body to recover and grow. There are many different ways to do
this - but the key is intensity. to GREATLY ENHANCE the process take
247BodyBuilder capsules and your muscle grow and strength will go into
overdrive. This is why 247BodyBuilder is the No.1 physique enhancing muscle
building sports nutritional supplement. Providing the most highly naturally
anabolic branched chain amino acid complex in a full strength capsule making
it the No.1 choice for anyone who is serious about adding
EXTREME MUSCLE SIZE & POWER FAST.

247Bodybuilder increases both
natural growth hormone and insulin levels, thereby increasing anabolism and
anti-catabolism. It also prevents a decrease in post-workout Testosterone
levels, and raises levels after exercise. In addition it decreases body fat ,
especially visceral fat, the fat that accumulates inside the abdomen.
What all of this means is that if you are serious about developing the BEST
PHYSIQUE that you can with bigger,
stronger muscles and less body fat then this is the "must have" supplement
for you.
BullWorker's 247BodyBuilder is an
enhanced, advanced anabolic formula designed for all serious weight lifters,
Rugby Player and bodybuilders looking to support increased strength and
muscularity!
The latest scientific research has been used to formulate this amazing
natural bodybuilding supplement with users reporting gains in muscle size and
strength enhancement on a par with chemical supplementation. Utilising the
potent amino acid leucine - the amazing natural anabolic supplement -
247BodyBuilder enhances protein synthesis and promotes a higher rate of
muscle growth and repair via the mTOR anabolic pathway for peak muscle
building. 247BodyBuilder utilizes an amazing naturally highly anabolic
4:1:1 branched chain amino acids ratio that contains four times the amount of
the leucine to isoleucine and valine for powerful strength and muscle
building, anti-catabolic muscle support, energy production and recovery.
Muscle Building
Supplements
BETTER THAN WHEY PROTEIN
- Ingestion of a supplement containing the active ingredients in
247Bodybuilder while following an 8-week resistance training program resulted
in a greater decrease in
percent
body fat, an increase in lean muscle size,
and 10-RM strength gains on the bench press and squat vs. ingestion of a whey
supplement or a sports drink. In addition, the ingestion of a whey protein
supplement resulted in greater lean mass gains than ingestion of a sports
drink.* (Jim Stoppani, et al., Journal of the International Society of Sports
Nutrition, 2009.) After exercise, recovery of muscle protein synthesis
benefits from BCAA's to increase tissue levels of leucine in order to release
the inhibition of the initiation factor 4 complex through the activation of
the protein kinase mammalian target of rapamycin (mTOR).* Leucine's effect on
mTOR is synergistic with insulin via the phosphoinositol 3-kinase signaling
pathway. Together, insulin and leucine allow skeletal muscle to coordinate
protein synthesis with physiological state and dietary intake.* (Layne Norton
and Donald Layman, Journal of Nutrition, 2006.)
Exercise may increase BCAA requirement, and BCAA supplementation before
exercise may reduce the breakdown of muscle proteins during exercise. Leucine
boosts protein synthesis in skeletal muscle, meaning that 247Bodybuilder
capsules reduce muscle damage
induced by exercise and promote recovery from the damage. Findings also
suggest that BCAA's may be useful for muscle recovery following intense
exercise, as BCAA supplementation before training decreased delayed-onset
muscle soreness after squatting exercise. (Yoshiharu Shimomura, et al.,
Journal of Nutrition, 2006.)
Supplementation with BCAA's was suggested to increase the lactate threshold
before exhaustion in high-intensity exercise on a cycle ergometer. Subjects
using BCAA's had noticeably higher plasma BCAA concentrations than the
non-supplemented group, in addition to higher respiratory exchange ratio and
both VO2 max and VO2 workload levels. These results suggest that BCAA
supplementation may be effective to increase endurance exercise capacity.
(Keitaro Matsumoto, et al., Journal of Nutritional Science Vitaminol, 2009.)
Exercise is known to deplete serum BCAA levels via oxidation. BCAA
supplementation before and after intense exercise has been suggested to
exhibit beneficial effects for decreasing exercise-induced muscle damage and
promoting muscle protein synthesis. This suggests that BCAA's are a useful
supplement in relation to exercise and sports. (Yoshiharu Shimomura, et al.,
Journal of Nutrition, 2004.)
Studies suggest that supplementation with leucine can both acutely and over a
longer period of time beneficially affect muscle protein anabolism. In
elderly adults, even small amounts of ingested leucine may acutely improve
muscle protein retention. The anabolic effect of extra leucine on muscle
protein was observed in the elderly and the response of muscle protein
synthesis following ingestion of small amounts of amino acids was surmised to
be greatly enhanced by additional leucine supplementation. (Christos Katsanos,
et al., American Journal of Physiological and Endocrinological Metabolism,
2006.)
247Bodybuilder is a high potency BCAA
4:1:1 supplement. Each bottle contains 180 capsules. Each dosage is 4
capsules providing 2,000mg Leucine ,
500mg Isoleucine and 500mg Valine. BUY ONE BOTTLE GET ANOTHER BOTTLE FREE.
In skeletal muscles
and the heart, BCAA supplementation alone, has the same benefits of
stimulating protein synthesis and reducing muscle breakdown, as is the case
when the supply of all amino acids is increased (May and Buse, 1989). BCAAs
supplementation has been demonstrated to preserve and even increase muscle
size under extreme physical conditions where there would normally be a net
loss of muscle tissue (Schena et al., 1992; Bigard et al., 1996). Research
looking at the effect of BCAA supplementation during prolonged skiing at
altitude, found that the consumption of BCAAs helped to prevent a loss of
body mass (Bigard et al., 1996). Research has also demonstrated a positive
effect on immune function with BCAAs supplementation (Bassit et al., 2000;
Bassit et al., 2002).
During aerobic exercise, or any prolonged exercise session, BCAAs can be
oxidized within the mitochondria of skeletal muscles to produce aerobic
energy – the six other essential amino acids are mainly catabolized within
the liver (Shimomura et al., 2004). It is well known that during aerobic
exercise – endurance exercise in particular – the level of BCAAs metabolised
to produce energy increases significantly (Rennie, 1996; Kobayashi et al.,
1999). Therefore, during any prolonged period of exercise, a significant
amount of BCAAs, may be metabolised and may lead to a depletion of BCAAs
within muscles.
It should also be noted that Zinc, Magnesium, and Vitamin B6 all have
positive effects on mood and may help to alleviate the low feeling sometimes
experienced during heavy training.
Research looking at the effect of BCAA supplementation has found that taking
77mg of BCAAs, per kg of bodyweight, before exercise results in a significant
reduction in the amount of muscle breakdown (MacLean et al., 1994). So to
reduce muscle breakdown during exercise a 70kg athlete would consume around
5g of BCAAs. It has also been demonstrated that the consumption of BCAAs
before and after exercise reduces the levels of serum creatine kinase
activity – which indicates reduced levels of muscle breakdown (Coombes and
McNaughton, 2000; Nosaka, 2003). BCAA supplementation before and after
exercise also appears to increase the recovery rate from exercise, as
indicated by a reduction in muscle soreness following exercise (Nosaka,
2003). Therefore, BCAA supplementation, before and after exercise, appears to
be beneficial for reducing the level of exercise-induces muscle damage and
for increasing muscle protein synthesis (muscle building) and enhancing the
recovery process following exercise.
A further benefit, is the positive effects that BCAAs supplementation appears
to have on endurance performance. BCAAs compete with the amino acid trytophan
for uptake into the brain. During prolonged exercise BCAAs are used for fuel
and this leads to a decreased level of BCAAs in the blood. The decreased
levels of BCAAs in the blood means there is a greater ratio of tryptophan
uptake into the brain. High levels of tryptophan in the brain, are associated
with increased feelings of tiredness and fatigue, and hence, reduced exercise
performance. Supplementation with BCAAs during exercise keeps the levels of
BCAAs elevated in the blood and helps to delay the build up of tryptophan in
the brain. Research suggests that supplementing with BCAAs during exercise
may have a positive effect on exercise performance by reducing fatigue (Blomstrand
et al., 1991).
BCAA Benefits – The Studies
A study evaluated the efficacy of a BCAA supplement in comparison to a whey
supplement or carbohydrate drink during eight-week resistance training. At
random, thirty-six strength trained males either received 28 grams of whey
protein or 14 grams of BCAAs or 28 grams of carbohydrates in an energy drink
during the workout. Body mass, body fat percentage and 10 RM on the barbell
bench press and barbell squat were tested before and after the eight-week
program. Statistical analysis of recorded data clearly established that
consumption of BCAA supplement during workouts led to a greater increase in
lean muscle mass, fat loss and 10RM strength on the barbell bench press and
barbell squat than whey or carbohydrate supplement. This study proved that
the BCAA powder benefits users by promoting fat loss, promoting muscle
growth, preventing fatigue, and maintaining strength. A significant benefit
associated with the intake of branched chain amino acids is the decrease in
muscle soreness after exercise. This means that BCAA supplementation results
in faster recovery from exercise-induced protein damage and gives an athlete
the opportunity to train harder.
BCAA Benefits – Lose Bodyfat
BCAA supplements benefit loss of visceral body fat that is present in deeper
layers of body and hard to shed. The body as an indication of excessive
muscle breakdown senses the higher BCAA levels during exercise. As a result,
it stops muscle disruption and starts using more fat as the energy source.
Moreover, BCAA increases insulin in the blood that it is utilized directly in
muscles. In a study, twenty-five wrestlers were divided into three diet
groups: high BCAA diet, low BCAA diet and control diet. They received the
respective diets for 19 days. It was found that, on average, high BCAA diet
group lost 17.3% body fat in the abdomen region. Thus, proper BCAA nutrition
can be effective in targeted fat loss. In another study, one group of
climbers was given BCAA supplements, while another group did not receive the
supplement. Body fat was reduced in both groups. However, there was loss of
muscle mass in those who did not receive BCAA supplements. Therefore, BCAAs
benefits include fat loss while increasing the lean muscle mass.
BCAA Benefits – Increase Endurance and Reduce Fatigue
For endurance athletes who are involved in exercises for more than 3hr., BCAA
supplements can help delay central fatigue and maintain mental activity.
Central fatigue can severely affect the physical performance. A noted reason
for central fatigue is increased level of 5-hydroxytryptamine (5-HT) in the
brain. 5-HT is produced from an amino acid, tryptophan, and this synthesis
depends upon the analogous concentration of tryptophan in the blood and the
brain. If tryptophan crosses the blood-brain barrier, and the concentration
is greater in the brain, there will be greater production of 5-HT, and thus,
greater fatigue. BCAAs play a role in reducing fatigue by competing with
tryptophan in crossing the blood-brain barrier. When BCAA are taken during
exercise, the blood level of BCCA increases, thereby reducing tryptophan
uptake in the brain as BCAA and tryptophan share the same carrier system.
This diminishes exercise associated fatigue. During a 30-km cross-country
race and a standardized cycle ergometer exercise, people who were given BCAA
showed less exertion and mental fatigue and performed well at different
cognitive tests after the activity.
BCAA Benefits – Immune System Health
Along with other benefits, BCAA supplements benefits include a stronger
immune system. After an illness, the body is too weak to resume physical
training and high volume exercise increases risk of infections and further
immune suppression. BCAAs augment the glutamine loss and prevent a catabolic
state by helping overcome damaging effects of exercise. Benefits of branched
chain amino acids extend to reducing inflammation and strengthening immune
system functioning after vigorous workouts.
References:
1.Borsheim E, Tipton KD, Wolf SE, Wolfe RR: Essential amino acids and muscle
protein recovery from resistance exercise.Am J Physiol Endocrinol Metab283
:E648-E657,2002.
2.Matthews DE. Observations of branched-chain amino acid administration in
humans. J Nutr. 2005;135:1580S-4S.
3.Anthony JC, Reiter AK, Anthony TG, et al. Orally administered leucine
enhances protein synthesis in skeletal muscle of diabetic rats in the absence
of increases in 4E-BP1 or S6K1 phosphorylation.. 2002;51(4):928-936.
4.Bianchi G, Marzocchi R, Agostini F, Marchesini G. Update on nutritional
supplementation with branched-chain amino acids. . 2005;8(1):83-87.
5.Yoshizawa F. Regulation of protein synthesis by branched-chain amino acids
. Biochem. Biophys. Res. Commun. 2004;313:417-422
6. Kraemer WJ, Ratamess NA, Volek JS, Hakkinen K, Rubin MR, French DN, Gomez
AL, et al. The effects of amino acid supplementation on hormonal responses to
resistance training overreaching. Metabolism. 2006 Mar;55(3):282-91.
7. Paddon-Jones D, Sheffield-Moore M, Katsanos CS, Zhang XJ, Wolfe RR.
Differential stimulation of muscle protein synthesis in elderly humans
following isocaloric ingestion of amino acids or whey protein. Exp Gerontol.
2006 Feb;41(2):215-9. Epub 2005 Nov 23.
8. Morifuji M, Sakai K, Sanbongi C, Sugiura K. Dietary whey protein increases
liver and skeletal muscle glycogen levels in exercise-trained rats. Br J Nutr.
2005 Apr;93(4):439-45.
9. Shimomura Y, Yamamoto Y, Bajotto G, Sato J, Murakami T, Shimomura N,
Kobayashi H, Mawatari K. Nutraceutical effects of branched-chain amino acids
on skeletal muscle. J Nutr. 2006 Feb;136(2):529S-32S.
10. Krieger JW, Sitren HS, Daniels MJ, Langkamp-Henken B. Effects of
variation in protein and carbohydrate intake on body mass and composition
during energy restriction: a meta-regression. Am J Clin Nutr. 2006
Feb;83(2):260 -74.
11.Bassit, R. A., Sawada, L. A., Bacurau, R. F. P., Navarro, F. and Costa
Rosa, L. F. B. P. (2000) The effect of BCAA supplementation upon the immune
system of triathletes. Medicine and Science in Sports and Exercise. 32,
1214-1219.
12.Bassit, R. A., Sawada, L. A., Bacurau, R. F., Navarro, F., Martins, E. Jr,
Santos, R. V., Caperuto, E. C., Rogeri, P. and Costa Rosa, L. F. (2002)
Branched-chain amino acid supplementation and the immune response of
long-distance athletes. Nutrition. 18 (5), 376-379.
13.Bigard, A. X., Lavier, P., Ulmann, L., Legrand, H., Douce, P. and
Guezennec, C. Y. (1996) Branched-chain amino acid supplementation during
repeated prolonged skiing exercises at altitude. Int J Sport Nutr. 6 (3),
295-306.
14.Blomstrand, E., Hassmen, P. and Ekblom, B. (1991) Administration of
branched-chain amino acids during sustained exercise-effects on performance
and on plasma concentration of some amino acids. European Journal of Applied
Physiology. 63, 83-88.
15.Coombes, J. S. and McNaughton, L. R. (2000) Effects of branched-chain
amino acid supplementation on serum creatine kinase and lactate dehydrogenase
after prolonged exercise. J Sports Med Phys Fitness. 40, 240-246.
16.Kobayashi, r. shimomura, Y., Murakami, T., Nakai, N., Otsuka, M., Arakawa,
N., Shimizu, K. and Harris, R. A. (1999) Hepatic branched-chain alpha-keto
acid dehydrogenase complex in female rats: activation by exercise and
starvation. J Nutr Sci. Vitaminol. 45, 303-309.
17.May, M. E. and Buse, M. G. (1989) Effects of branched chain amino acids on
protein turnover. Diab Metab Rev. 5 (3), 227-245.
18.MacLean, D. A., Graham, T. E. and Saltin, B. (1994) Branched-chain amino
acids augment ammonia metabolism while attenuating protein breakdown during
exercise. Am J Physiol. 267, E1010-E1022.
19.Nosaka, K. (2003) Muscle soreness and amino acids. Training J. 289, 24-28.
20.Rennie, M. J. (1996) Influence of exercise on protein and amino acid
metabolism. In: Handbook of Physiology, Sect 12: Exercise: Regulation and
Integration of Multiple Systems (Rowell, L. B. & Shepherd, J. T., eds),
Chapter 22. 995-1035. American Physiological Society, Bethesda, MD.
21.chena, F., Guerrini, F. and Tregnaghi, P. (1992) Branched-chain amino acid
supplementation during trekking at altitude. The effects on loss of body
mass, body composition, and muscle power. European Journal of Applied
physiology. 65, 394-398.
22.Shimomura, Y., Murakami, T., Nakai, N., Nagasaki, M. and Harris, R. A.
(2004) Exercise Promotes BCAA Catabolism: Effects of BCAA Supplementation on
Skeletal Muscle during Exercise. J Nutr. 134, 1583S-1587S.
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